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| Optimizing Application Driven Multimodality Spatio-Temporal Emission Imaging Molecular Medicine seeks the understanding of health and disease at the cellular
and molecular level, and to use this information to design new approaches to
promote health and prevent, diagnose, cure and treat disease. Molecular imaging
visualizes and localizes molecular processes in vivo for diagnosis and therapy.
Currently volumetric imaging has become clinical practice, however the current
clinical protocol either assumes a quasi-static distribution and thus the
temporal averaging of distribution variations, or uses sequential acquisitions
in small time steps of the tracer distribution to assess its temporal variation
("dynamic" 3+1D acquisition). Active research is conducted to acquire, process
and analyze spatio-temporal consistent and inconsistent tomographic datasets
and to assess the benefits in clinical applications. This research project aims
to both prepare the foundation of quantitative objective spatio-temporal image
quality assessment and to apply such methods to 3+1 D and fully 4D methods, yet
to be developed. The methods will be applied to selected clinical applications. | Project manager:
Prof. Dr.-Ing. Joachim Hornegger, Prof. Dr. med. Torsten Kuwert, Hans Vija
Project participants:
Dr.-Ing. Johannes Zeintl
Keywords:
Molecular Imaging; Dynamic Imaging; Image Quality Analysis
Duration: 1.4.2007 - 30.3.2010
Sponsored by:
Siemens Medical Solutions USA, Inc., Molecular Imaging
Contact:
Zeintl, Johannes
E-Mail: johannes.zeintl@uk-erlangen.de
| | Publications |
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| Vija, A. Hans ; Zeintl, Johannes ; Chapman, James T. ; Hawman, Eric G. ; : Development of Rapid SPECT Acquisition Protocol for Myocardial Perfusion Imaging. In: Smith, Graham C. (Ed.) : Nuclear Science Symposium, Medical Imaging Conference 2006 (2006 IEEE Nuclear Science Symposium, Medical Imaging Conference San Diego (USA) 29. Oktober - 4. November 2006). 2006, pp 1811-1816. | | Zeintl, Johannes ; Vija, A. Hans ; Chapman, James T. ; Hawman, Eric G. ; : Quantifying the Effects of Acquisition Parameters in Cardiac SPECT Imaging and Comparison with Visual Observers. In: Smith, Graham C. (Ed.) : Nuclear Science Symposium, Medical Imaging Conference 2006 (2006 IEEE Nuclear Science Symposium, Medical Imaging Conference San Diego (USA) 1.-4. November 2006). 2006, pp 3251-3257. | | Zeintl, Johannes ; Ding, Xinhong ; Vija, A. Hans ; Hawman, Eric G. ; ; Kuwert, Torsten: Estimation Accuracy of Ejection Fraction in Gated Cardiac SPECT/CT Imaging using Iterative Reconstruction with 3D Resolution Recovery in Rapid Acquisition Protocols. In: IEEE (Org.) : Nuclear Science Symposium, Medical Imaging Conference 2007 (2007 IEEE Nuclear Science Symposium, Medical Imaging Conference Honolulu (USA) 28.10.2007- 3.11.2007). 2007, pp 4491-4496. | | Zeintl, Johannes ; Vija, A. Hans ; Yahil, Amos ; Ding, Xinhong ; ; Kuwert, Torsten: Towards Quantitative SPECT: Error Estimation of SPECT OSEM with 3D Resolution Recovery, Attenuation Correction and Scatter Correction. In: Sellin, Paul (Ed.) : Nuclear Science Symposium, Medical Imaging Conference 2008 (Nuclear Science Symposium, Medical Imaging Conference 2008 Dresden 19 - 25 October 2008). 2008, pp 4106-4111. | | Zeintl, Johannes ; Vija, A. Hans ; Yahil, Amos ; ; Kuwert, Torsten: Quantitative Accuracy of Slow-Rotating Dynamic SPECT. In: Yu, Bo (Ed.) : Nuclear Science Symposium, Medical Imaging Conference 2009 (IEEE Nuclear Science Symposium, Medical Imaging Conference 2009 Orlando, USA 25 - 31 Oktober 2009). 2009, pp 3853-3857. - ISBN 978-1-4244-3962-1 |
Institution: Chair of Computer Science 5 (Pattern Recognition)
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