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Biomaterials and Bioprocessing 2 (PF MAP-S-BMP 3)7.5 ECTS (englische Bezeichnung: Biomaterials and Bioprocessing 2)
(Prüfungsordnungsmodul: Schwerpunktfach Biomaterials and Bioprocessing 2)
Modulverantwortliche/r: Aldo R. Boccaccini Lehrende:
Stephan E. Wolf, Aldo R. Boccaccini, Rainer Detsch, Joachim Kaschta
Startsemester: |
WS 2017/2018 | Dauer: |
1 Semester | Turnus: |
jährlich (WS) |
Präsenzzeit: |
90 Std. | Eigenstudium: |
135 Std. | Sprache: |
Englisch |
Lehrveranstaltungen:
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Biomimetic synthesis of materials
(Vorlesung, 2 SWS, Stephan E. Wolf, Mo, 10:15 - 11:45, 0.15)
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Application of Cell Technology
(Vorlesung, 2 SWS, Aldo R. Boccaccini et al., Mi, 8:30 - 10:00, SemR-USS)
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Polymerwerkstoffe in der Medizin
(Vorlesung, 2 SWS, Joachim Kaschta, Mo, 12:15 - 13:45, 1.84)
Inhalt:
Application of cell technology:
basics of cell-biomaterial interactions
protein-, cell-, blood-surface interactions
inflammation and wound healing
bioactivity and surface bioreactivity
biocompatibility - basics of cell cultures and stem cells
Case studies: tissue engineering - hard tissue
Case studies: tissue engineering - soft tissue
Biomimetic Synthesis of Materials:
The course "Biomimetic Materials and Processing" introduces to the principles of growth, form and evolutionary optimisation strategies.
Basic biochemical and microbiological in respect to self-assembly, stimuli-response and adaptation are covered.
The key properties and functions biominerals are discussed.
The fundamental biomineralisation processes are introduced
Bio-inspired concepts and processes for manufacturing biomimetic, inorganic functional materials are presented.
The course is completed leading through smart materials and application prospects of biomimetic materials.
INTRODUCTION
FUNDAMENTAL ASPECTS OF BIOLOGICAL MATERIALS
BASICS IN BIOCHEMISTRY
BIOMINERALISATION AND BIOMINERALS
BIOINSPIRED STRATEGIES FOR INORGANIC MATERIALS PROCESSING
Principles, Powders, 1D Templates: fibers, 2D Structure & surface mineralization, 3D Assemblies & cellular composites, Biotemplating & genetic engineering
POTENTIAL APPLICATIONS
Polymers in Medical Application:
overview on polymers in medical applications
polymers and polymer composites in bone replacement and artificial joints
resorbable polymers in implants – biodegradability of polymers
polymers in drug delivery systems
polymers for medical applications with blood contact (artificial blood vessels, artificial heart valves, artificial hearts,) – thrombogenicity of polymer surfaces.
sterilization of polymers
antimicrobial polymers
polymers for catheters
polymer and polymer composites for dental applications
scaffolds from polymers for tissue engineering
polymers for sinews and ligament replacement
Lernziele und Kompetenzen:
Application of Cell Technology:
The lecture enables the students the knowledge of the application of cell techniques for tissue engineering in regenerative medicine
Biomimetic Materials:
The lecture enables the students …
to elaborate differences between bionic and biomimetic sciences
identify the basic principles of biological materials and their assembly in biological processes, esp. biominerals and biomineralisation
to transfer fundamental knowledge on cells and the biopolymers involved in biomineral formation for materials synthesis
how to generate a new class of materials using biological principles
Polymers in Medical Application:
The lecture enables the students to understand which factors from the polymer structure (chemical as well as molecular) determine the use of certain polymers in a selected medical application.
The student will learn how to choose a polymer for a given medical application.
Additionally, ways of modifying polymers for certain applications are discussed (e.g. reinforcement, surface modification) together with its theoretical background.
The student gets insight into structure-property relationships being relevant for medical applications of polymers.
Literatur:
Application of Cell Technology:
-- Di Silvio (ed.): Cellular Response to Biomaterials; Cambridge u.a., 2009
KC Dee, DA Puleo and R Bizios: Tissue-Biomaterial-Interaction; Wiley-Liss New Jersey, ISBN 0-471-25394-4
B. D. Ratner et al. (eds.): Biomaterials Science, 2nd Ed., Elsevier, 2004.
Biomimetic Materials:
E Bäuerlein, Biomineralization, Wiley-VCH (2004)
TX Fan, SK Chow, D Zhang, Biomorphic mineralization: From biology to materials, Progress in Materials Science 54 (2009) 542–659
P Gomez-Romero, C Sanchez Functional Hybrid Materials, Wiley-VCH (2004)
Polymers in Medical Applications:
Wintermantel E.; Ha, S.W.; Medizintechnik – Life Science Engineering, Springer, 5th. ed. 2009
Mahapatro A. (ed.); Polymers for biomedical applications 2nd ed. Oxford, 2005 ....
Bemerkung:
Beginn ab KW 43
Verwendbarkeit des Moduls / Einpassung in den Musterstudienplan:
- Advanced Materials and Processes (Master of Science with Honours)
(Po-Vers. 2014w | TechFak | Advanced Materials and Processes (Master of Science with Honours) | Masterprüfung | Schwerpunktfächer | Schwerpunktfach Biomaterials and Bioprocessing 2)
Studien-/Prüfungsleistungen:
Biomimetic Materials and Processes (Prüfungsnummer: 1921)
(englischer Titel: Biomimetic Materials and Processes)
zugeh. "mein campus"-Prüfung: | - 1921 Biomimetic Synthesis of Materials (Gewichtung: 0.0 %, Prüfung, Form: mündliche Prüfung, Drittelnoten (ohne 4,3), Dauer: -, 2.5 ECTS, Prüfung).
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- Untertitel: Biomimetic synthesis of materials
(englischer Untertitel: Biomimetic synthesis of materials)
- Prüfungsleistung, mündliche Prüfung, Dauer (in Minuten): 10, benotet
- Anteil an der Berechnung der Modulnote: 0.0 %
- Prüfungssprache: Englisch
- Erstablegung: WS 2017/2018, 1. Wdh.: SS 2018
1. Prüfer: | Stephan E. Wolf (100559) |
Application of Cell Technology (Prüfungsnummer: 1922)
(englischer Titel: Application of Cell Technology)
zugeh. "mein campus"-Prüfung: | - 1922 Application of Cell Technology (Gewichtung: 0.0 %, Prüfung, Form: mündliche Prüfung, Drittelnoten (ohne 4,3), Dauer: -, 2.5 ECTS, Prüfung).
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- Untertitel: Application of Cell Technology
- Prüfungsleistung, mündliche Prüfung, Dauer (in Minuten): 10, benotet
- Anteil an der Berechnung der Modulnote: 0.0 %
- Prüfungssprache: Englisch
- Erstablegung: WS 2017/2018, 1. Wdh.: SS 2018
1. Prüfer: | Aldo R. Boccaccini (100550) |
Polymerwerkstoffe in der Medizin (Prüfungsnummer: 1923)
(englischer Titel: Polymeric Materials in Medicine)
zugeh. "mein campus"-Prüfung: | - 1923 Polymerwerkstoffe in der Medizin (Gewichtung: 0.0 %, Prüfung, Form: mündliche Prüfung, Drittelnoten (ohne 4,3), Dauer: -, 2.5 ECTS, Prüfung).
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- Prüfungsleistung, mündliche Prüfung, Dauer (in Minuten): 10, benotet
- Anteil an der Berechnung der Modulnote: 0.0 %
- Prüfungssprache: Englisch
- Erstablegung: WS 2017/2018, 1. Wdh.: SS 2018
1. Prüfer: | Joachim Kaschta (100556) |
- Termin: 22.02.2018, 09:00 Uhr, Ort: 1.68
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