Medicinal chemistry A (Pharmaceutical chemistry) (MSM-ME5A)15 ECTS
(englische Bezeichnung: Medicinal chemistry A (Pharmaceutical chemistry))
(Prüfungsordnungsmodul: Wahlpflichtmodul Molecular Science)

Lectures:

• A1: Pharmacopoeia-based analysis of bioactive compounds (1L + 1L)
  • Pharmazeutisch-medizinische Analytik II/Pharmacopeia based analysis (WS 2018/2019)
    (Vorlesung, 1 SWS, Jutta Eichler, Mon, Fri, 9:15 - 10:00, C4 - Chemikum; Tue, 10:15 - 11:00, C2 - Chemikum; Beginn: Montag, 15.10.2018)
  • Pharmazeutisch-medizinische Analytik III (SS 2019)
    (Vorlesung, 1 SWS, Jutta Eichler, Tue, 10:00 - 11:00, C3 - Chemikum; starting 30.4.2019)
• A2: Pharmaceutical/Medicinal Chemistry (3 L + 3L)
  • Medizinische Chemie B1 (5.+7. Semester) / Medical Chemistry (WS 2018/2019)
    (Vorlesung, 3 SWS, Peter Gmeiner, Tue, Wed, Thu, 9:00 - 10:00, C2 - Chemikum; Einführungsveranstaltung für Studierende Molecular Science Bachelor: Donnerstag, 18.10.2018 9:15 Uhr , Beginn der Vorlesung : Dienstag, 23.10.2018)
  • Medizinische Chemie B2 (6.+8. Semester) (SS 2019)
    (Vorlesung, 3 SWS, Peter Gmeiner, Tue, Wed, Thu, 9:00 - 10:00, C2 - Chemikum; starting 25.4.2019)
• A3: Pharmacopoeia-based analysis of bioactive compounds (7 Lab)

  Attendance in lab courses is compulsory!

  • Praktikum Arzneibuchanalytik / Practical Pharmacopeia based Analysis (WS 2018/2019)
    (Praktikum, 7 SWS, Jutta Eichler et al., every week Mon, Tue, Wed, Thu, 12:00 - 18:00, Raum n.V.; Fri, 12:00 - 15:00, Raum n.V.; Vorbesprechung/Introduction:; Preliminary meeting: 16.10.2018, 10:00 - 12:00 Uhr, C4 - Chemikum)

Inhalt:

A1: General, as well as substance-specific methods for the qualitative and quantitative analysis (identity, purity, concentration) of drug substances according to the European Pharmacopeia; assessment of physico-chemical properties and reactivities of drug substances, based on their structures; evaluation of the informational value (selectivity, specificity) of individual analysis methods/reactions; special focus: color reactions.
A2: Theoretical knowledge and understanding for the mechanism of action, chemical synthesis, biotransformation, physikochemical properties and SAR studies of the most important drugs and bioactive compound families including: Agents affecting the nervous system, agents with cardiovascular effects, antiallergics, analgesics, antidiabetics, antibiotics, chemotherapeutics and vitamins.
A3: lab course on the pharmaceutical analysis of drugs; determination of identity, purity and quantification

Lernziele und Kompetenzen:

The students

• gain insight into the design, synthesis & development of new drug products in the medicinal/pharmaceutical area

• acquire expertise for the theoretical evaluation and practical application of the most important techniques for the instrumental and bioanalysis of drugs

• are able to reflect crucial theories of the specialty in order to challenge problems in analytical practice.

Bemerkung:

Intended stage in the degree course: Mandatory elective module (Wahlpflichtmodul) or Elective module (Wahlmodul)
Courses of study for which the module is acceptable: M.Sc. Molecular Life Science

Organisatorisches:

Frequency of offer: annually (starts only in winter term!)
A3: winter term, A1/A2: winter & summer term,

Language:
English: A3; German: A1, A2

Verwendbarkeit des Moduls / Einpassung in den Musterstudienplan:

1. Molecular Science (Master of Science)
   (Po-Vers. 2013 | NatFak | Molecular Science (Master of Science) | Wahlpflichtmodul Molecular Science)

Studien-/Prüfungsleistungen:

Medizinische Chemie - Ausrichtung Pharmazeutische Chemie (Prüfungsnummer: 30808)

(englischer Titel: Medicinal Chemistry – Focus: Pharmaceutical Chemistry)

Prüfungsleistung, mündliche Prüfung, Dauer (in Minuten): 45, benotet

Anteil an der Berechnung der Modulnote: 100.0 %

weitere Erläuterungen:
Assessment and examinations: O45 (PL)+ LAB (SL): oral examination (45 min, 2 examiners)+ lab course protocol(s), ungraded,+ presentation
Calculation of the grade for the module: 100% from oral examination

Prüfungssprache: Deutsch

Erstablegung: SS 2019, 1. Wdh.: WS 2019/2020

1. Prüfer:

Monika Pischetsrieder