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Retrospective Motion Compensation in Optical Coherence Tomography Optical coherence tomography (OCT) opens up the possibility
to perform
non-invasive, in vivo, micron scale 2D and 3D imaging of
scattering tissue, such
as the retina. Using 3D-OCT, quantitative measurements can
be performed in
ophthalmology, facilitating early detection and treatment of
eye diseases, such
as glaucoma and diabetic retinopathy. 3D-OCT datasets are
not acquired
instantaneously but are composed of many 1D axial scans
recorded within few
seconds. Thus, datasets show distortions and artefacts that
result from motion
of the eye during the scan. OCT images also contain speckle
noise. We approach
these problems by using multiple 3D scans of an area which
are registered with
each other to correct for motion and are combined so that
speckle noise is
reduced. OCT images with different scanning patterns are
used to retrospectively
estimate and compensate object motion. A novel software only
registration method
based on the optimization of a global, problem-specific
objective function that
is able to correct motion in all three dimensions is
proposed. It offers great
potential for achieving both more accurate data and improved
image quality
without the additional cost and complexity of hardware based
motion correction
methods. The ability to accurately and repeatably image the
retina could improve
the early, accurate diagnosis of disease and monitoring of
treatment.
| Project manager: Prof. Dr.-Ing. Joachim Hornegger, Prof. Dr. Christian Y. Mardin, Prof. Dr. med. Friedrich E. Kruse
Project participants: Dr.-Ing. Martin Kraus
Keywords: Optische Kohaerenztomographie; Bildregistrierung; Bewegungskorrektur; Signalverbesserung; Medizinische Bilddaten
Duration: 1.7.2013 - 30.6.2014
Sponsored by: Deutsche Forschungsgemeinschaft
Mitwirkende Institutionen: Augenklinik Erlangen Massachussets Institute of Technology
Contact: Kraus, Martin
| Publications |
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Liu, Jonathan J. ; Grulskowski, Ireneusz ; Potsaid, Benjamin M. ; Jayaraman, Vijaysekhar ; Cable, Alex E. ; Kraus, Martin ; Hornegger, Joachim ; Duker, Jay S. ; Fujimoto, James G.: 4D dynamic imaging of the eye using ultrahigh speed SS-OCT. In: SPIE (Ed.) : Proc. SPIE 8567 (Ophthalmic Technologies XXIII San Francisco 02.02.2013). 2013, pp 85670X. [doi>10.1117/12.2004369] | Kajic, Vedran ; Esmaeelpour, Marieh ; Glittenberg, Carl ; Kraus, Martin ; Hornegger, Joachim ; Othara, Richu ; Binder, Susanne ; Fujimoto, James G. ; Drexler, Wolfgang: Automated three-dimensional choroidal vessel segmentation of 3D 1060 nm OCT retinal data. In: Biomedical Optics Express 4 (2013), No. 1, pp 134-150 [doi>10.1364/BOE.4.000134] | Köhler, Thomas ; Budai, Attila ; Kraus, Martin ; Odstrcilik, Jan ; Michelson, Georg ; Hornegger, Joachim: Automatic No-Reference Quality Assessment for Retinal Fundus Images Using Vessel Segmentation. In: IEEE (Ed.) : 2013 26th IEEE International Symposium on Computer-Based Medical Systems (CBMS) (International Symposium on Computer-Based Medical Systems Porto, Portugal 2013). 2013, pp 95-100. [doi>10.1109/CBMS.2013.6627771] | Liu, Jonathan J. ; Grulskowski, Ireneusz ; Kraus, Martin ; Potsaid, Benjamin ; Lu, Chen D. ; Baumann, Bernhard ; Duker, Jay S. ; Hornegger, Joachim ; Fujimoto, James G.: In vivo imaging of the rodent eye with swept source/Fourier domain OCT. In: Biomedical Optics Express 4 (2013), No. 2, pp 351-363 [doi>10.1364/BOE.4.000351] | Ahsen, Osman O. ; Tao, Yuankai K. ; Potsaid, Benjamin M. ; Sheikine, Yuri ; Jian, James ; Grulkowski, Ireneusz ; Tsa, Tsung-Han ; Jayaraman, Vijaysekhar ; Kraus, Martin ; Connolly, James L. ; Hornegger, Joachim ; Cable, Alex ; Fujimoto, James G.: Swept source optical coherence microscopy using a 1310 nm VCSEL light source. In: Optics Express 21 (2013), No. 15, pp 18021-18033 [doi>10.1364/OE.21.018021] | Tsai, Tsung-Han ; Tao, Yuankai K. ; Potsaid, Benjamin M. ; Jayaraman, Vijaysekhar ; Kraus, Martin ; Heim, Peter J. S. ; Hornegger, Joachim ; Mashimo, Hiroshi ; Cable, Alex E. ; Fujimoto, James G.: Ultrahigh speed endoscopic optical coherence tomography using micro-motor imaging catheter and VCSEL technology. In: SPIE (Ed.) : Proc. SPIE 8571 (Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XVII San Francisco, California, USA 02.02.2013). 2013, pp 85710N. [doi>10.1117/12.2006952] |
Institution: Chair of Computer Science 5 (Pattern Recognition)
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