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ILS-MA-I2A: Interaction of Biological Macromolecules A (ILS-MA-I2A)5 ECTS (englische Bezeichnung: ILS-MA-I2A: Wechselwirkungen von Biologischen Macromolekülen A)
Modulverantwortliche/r: Yves Muller Lehrende:
Yves Muller, Petra Dietrich, Jutta Eichler, Heinrich Sticht
Startsemester: |
WS 2022/2023 | Dauer: |
1 Semester | Turnus: |
jährlich (WS) |
Präsenzzeit: |
60 Std. | Eigenstudium: |
90 Std. | Sprache: |
Englisch |
Lehrveranstaltungen:
Empfohlene Voraussetzungen:
none
Inhalt:
Lectures and Tutorials cover topics of interactions between biological macromolecules extending from protein-protein to protein-DNA and protein-ligand interactions. The following topics will be discussed: Energetic and thermodynamic contributions, the description of structural determinants, the use of homology modelling, the prediction of contiguous and non-contiguous interaction sites in proteins, experimental methods for studying interactions, the analysis of interaction surfaces via peptide mapping as well as selected examples of protein interactions involved in plant signalling networks.
Lernziele und Kompetenzen:
The students will
acquire an in-depth knowledge of structure-function relationships in interacting macromolecules
be able to assess the suitability of current experimental methods such as X-ray crystallography, NMR, peptide mapping, ITC and SPR for studying protein-protein and protein-ligand interactions.
become familiar with bioinformatics methods to predict and analyse interactions between biological macromolecules.
gain fundamental knowledge in plant signalling networks
be able to present and critically discuss current research articles
be able to discuss their results and defend their conclusions in proper context
extended their capacity for teamwork and their communication as well as social competence
Literatur:
none
Verwendbarkeit des Moduls / Einpassung in den Musterstudienplan: Das Modul ist im Kontext der folgenden Studienfächer/Vertiefungsrichtungen verwendbar:
- Integrated Life Sciences: Biology, Biomathematics, Biophysics (Master of Science)
(Po-Vers. 2019w | NatFak | Integrated Life Sciences: Biology, Biomathematics, Biophysics (Master of Science) | Module Groups | MG3: Biological Structures and Processes | Interactions of Biological Macromolecules A)
Studien-/Prüfungsleistungen:
Interactions of Biological Macromolecules A (Prüfungsnummer: 81211)
- Prüfungsleistung, mehrteilige Prüfung, benotet
- Anteil an der Berechnung der Modulnote: 100.0 %
- weitere Erläuterungen:
PL: written exam 90 min.
SL: exerise sheets
- Erstablegung: WS 2022/2023, 1. Wdh.: SS 2023
1. Prüfer: | Böckmann/Muller |
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