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Structural Biology II: Structure and function relationships in biological macromolecules (StrBio2)7.5 ECTS (englische Bezeichnung: Strukturbiologie II: Struktur-Funktionsbeziehungen in Biologischen Makromolekülen)
Modulverantwortliche/r: Yves Muller Lehrende:
Rainer Böckmann, Yves Muller, Benedikt Schmid
Start semester: |
SS 2018 | Duration: |
1 semester | Cycle: |
jährlich (SS) |
Präsenzzeit: |
120 Std. | Eigenstudium: |
105 Std. | Language: |
Englisch |
Lectures:
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Mastermodul Biotechnik II: Structure und function relationships in biotechnologically relevant macromolecules
(Übung, 6 SWS, Yves Muller, single appointment on 3.4.2018, 9:15 - 10:45, Hörsaal ZMPT; single appointment on 4.4.2018, 9:15 - 10:15, Hörsaal ZMPT; single appointment on 5.4.2018, 9:15 - 10:45, Hörsaal ZMPT; single appointment on 6.4.2018, 9:15 - 10:15, Hörsaal ZMPT; single appointment on 9.4.2018, single appointment on 11.4.2018, single appointment on 12.4.2018, 9:15 - 10:45, Hörsaal ZMPT; single appointment on 16.4.2018, single appointment on 18.4.2018, 9:15 - 10:00, Hörsaal ZMPT; single appointment on 23.4.2018, 9:15 - 12:00, Hörsaal ZMPT; single appointment on 27.4.2018, 13:15 - 14:45, SR Biologie; Weitere Details zum Programm werden während der Veranstaltung bekannt gegeben.)
Empfohlene Voraussetzungen:
none
Inhalt:
Seminar talks cover theoretical and methodological approaches for the study of structure-function relationships in proteins with a focus on structural determinants in regulation of protein function. Laboratory course are focused on advanced methods in the study of structure-dynamics-function relationships of proteins. Both experimental (heterologous protein production in eucaryotic cells, X-ray analysis, mutation studies) as well as theoretical methods (atomistic and coarse-grained molecular dynamics simulations) will be addressed. The main part of the practical course is devoted to active cooperation in ongoing research projects of the participating labs.
Lernziele und Kompetenzen:
The students are
acquainted with novel insights, concepts, and methods in the study of protein-dynamics-function relationships
understand state-of-the-art methods in the analysis of protein structure, dynamics, function and their limitations
are able to independently develop working hypotheses, to independently design and conduct experiments
able to present and critically discuss current research articles / their results and defend their conclusions in proper context
Literatur:
introductory articles will be provided electronically
Verwendbarkeit des Moduls / Einpassung in den Musterstudienplan: Das Modul ist im Kontext der folgenden Studienfächer/Vertiefungsrichtungen verwendbar:
- Zell- und Molekularbiologie (Master of Science)
(Po-Vers. 2015w | NatFak | Zell- und Molekularbiologie (Master of Science) | Mastermodule | Biologische Mastermodule | Structural Biology II: Structure und Function Relationships in Biotechnologically Relevant Macromolecules)
Studien-/Prüfungsleistungen:
Portfolio exam Structural Biology II: Structure and Function Relationships in Biotechnologically Relevant Macromolecules (Prüfungsnummer: 22111)
- Prüfungsleistung, mehrteilige Prüfung, benotet, 7.5 ECTS
- Anteil an der Berechnung der Modulnote: 100.0 %
- weitere Erläuterungen:
PL: Schriftliche Prüfung (30 Min.)
PL: mündlicher Seminarvortrag (20 Min.)
PL: schriftliches Protokoll (ca. 30 Seiten)
- Erstablegung: SS 2018
1. Prüfer: | Böckmann/Muller |
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